The chart below indicates the most economical blood type to use, based on current market pricing (March 2023).
| Your blood type | To heal, use: | To self-hosp, use: |
| O+ | O+ | A+ |
| A+ | A+ | B+ |
| B+ | O+ | A+ |
| AB+ | A+ | ipecac |
| O- | O- | A+ |
| A- | A- | O+ |
| B- | O- | O+ |
| AB- | A- | O+ |
The chart below shows frequency, current market value and circulation (as of March 2023).
Edit: Updated pricing and circulation as of Feb 2026.
| Blood type | Frequency | Market value (thousands) | Circulation (millions) |
| O+ | 35% | 18 | 10.0 |
| A+ | 30% | 18 | 11.4 |
| AB+ | 2% | 19 | 1.5 |
| Irradiated | - | 52 | 0.3 |
| A- | 8% | 20 | 2.9 |
| B+ | 8% | 19 | 3.1 |
| O- | 13% | 22 | 3.5 |
| AB- | 1% | 24 | 0.8 |
| B- | 2% | 26 | 1.2 |