Flower running

Can somebody suggest the best flower and destination in terms of making profit (Not concerned about energy and nerve)

Best option is to unlock the museum, do longer runs, and buy the flowers you don't run, convert them, then sell the points. Points can be easier to sell than flowers...

Otherwise, the most profitable runs can vary every day, so there's no single answer...

Nope, depends on the value of the item and which time you want to invest. I tried to make several calculations but since they are all loose variables, I can't put a nail on it.

So f!or example I'm just doing the Argentina run, this fits best in my life-routine!

This wonderful guide has a link to a calculator sheet that shows the profit for every flower and plushie and also the profit per piece per hour and the total profit per flight.
It helped me a lot and the sheet seems to be updated at least once a week (if not you could insert current prices yourself) so it is pretty helpfull in my opinion.
Combine it with the travelrun site so you wont fly to a country that is out of stock and nothing should stop you from maximizing your profit :)

edit: looks like monkey plushies are the best at the moment, followed by peonies

Flower running isnt THAT simple. To male best use of your time you have to work with whats in stock, cooldowns, rl duties etc...

So to maximise your profits id say go at it one flight at a time....where are flowers left, how much time do you have, do you sleep tonight or just have another red bull?...and so on

Yup, long flights when I'm at work or can't login for a while or just need a nap.

Short hops when I know I can be here to refuel the cub cadet and get back in the air.

If I get a choice I pick a plushie. The flowers are in every destination and their supply is 4 times bigger. It triggers the value down a bit. You have got to be lucky sometimes as plushies are not on travelrun graphs.

hmmmm. odd question to ask really, all the info you need is at your hands, unless you really don't know the equation.... but see the below equation to help get the answer you seek

Profit = Revenue from Sale - Less Cost of Goods Sold

Example:
Flower A Cost $500
Place Flower A in bazaar for $54,000
Profit = $53,500

Good practice for you, not just with flowers, but with any items in this ol' game
Research the items, what they cost & what they sell for
Simply review the costs of all the flowers and then review the selling prices in the item/bazaar markets
Probably best to look at and review the item/bazaar market prices over a period of a day or a week, as the prices fluctuate throughout the day and depending on your timing and patience level, you can sell at a particular price, or you can just sell at the cheapest available price at the time you decide to sell.

But if you're looking for easy answer to your question, if energy and nerve are of no concern, travel to the farthest location to get flowers for the most profit -OR- alternatively travel to the mid range locations multiple times (in the same amount of time to travel to the farther location and back, you could potentially travel several times and back to the mid range locations). Pure profit on a particular flower = travel to the farthest locations. Best profit for you as an individual = completely dependent on how you time your travels.

Though yes Profit = Revenue - COGS (shush nobody cares about accounting language)

You forgot that travelling also costs time. So its better to aim for profit/hr instead of just pure profit (depending on availability of stock and sleep schedule).

I personally enjoy UK, if there are no flowers, there are two plushie options as well. Always able to get something for the travel.