This got me thinking about whether the current odds were evenly balanced - is there a selection that yields better expected results than the others? The following tables summarize the results. The first is a payout table from the casino, the second is the calculated odds of any given combination, and the third simply multiplies the two to give an expected average result, then sums all the possibilities up for a total expected average payout.
The best odds are only picking 1 number - your expected payout is even then, but it's also not very large. If you want a bit more excitement, your best bet would be to pick 6 numbers - your expected average loss would only be $240 on a $100,000 bet.
Note: this of course assumes the number selection is actually random. If there are some numbers that get hit with a higher frequency, even if small, the odds are close enough that you could likely tilt it in your favor. However - I have no evidence one way or another on that, so we'll assume the numbers are random.
TL;DR - If you care about winning money in the long run, Keno is not the game for you. If you want to play a game with only a slight house advantage and like the idea of big possible payouts, go ahead and play, but the chances of winning 10B by getting more than 7 out of 10 is so small that no one has yet gotten it in 27 million turns played.
[image: snipboard.io]
[image: snipboard.io]
[image: snipboard.io]
Also... just for fun, I did the odds table expressed as a 1 in X chance, so you can see how absurdly unlikely it is to get the big payouts
[image: snipboard.io]